【摘要】 目的探讨美肠安治疗腹泻型肠易激综合征的疗效。方法将60例患者随机分为2组,A组30例,口服得舒特50 mg,每天3次。B组30例,口服美常安500 mg,每天3次,得舒特50 mg,每天3次,疗程4周。观察大便性状评分,腹部综合症状等级评分和疗效评价。结果治疗4周后,两组Bristol评分均较治疗前明显提高,腹部症状评分较治疗前都有明显下降,B组改善更明显。两组之间的治疗效果比较有明显差异,B组疗效更好。结论美肠安治疗腹泻型肠易激综合征安全有效。更多还原

【Abstract】 Objective To evaluate the clinical efficacy of pinaverium bromid alone or combined with medilac-s in relieveng symptoms in patients with diarrhea-dominart irritable bowel syndrome(IBS-D).Methods 60 patients diagnosed as IBS-D according to the Rome Ⅲ criteria by a simple stool description were randomly divided into two groups.Group A(30 patients) received only pinaverium bromid alone(50 mg tid).Group B(30 patients)received pinaverium bromide combined with medilac-s(500 mg tid).Main outcomes assessment included the days of diarrhea,abdominal pain relief,the Bristol stool form scale,the symptomatic scores and curative effect at the end of 4 weeks.Results 4 weeks later,the Bristol stool from scale,the symptomatic score significantly improved in both groups comparing with baseline.In group B improvement was better than group A.There was significant difference of efficiency between group A and group B.Conclusion Medilac-s is an effective and safe agent for treatment of IBS-D更多还原