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美沙酮维持治疗者药物滥用因素对脱失的影响与对策

The Influence of Drug-Abuse-Related Factors on the Loss of Methadone Maintenance Treatment Patients and the Countermeasures

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【作者】 闵建华蔡军周小军陈红夏军强李国恩

【Author】 MIN Jian-hua1,CAI Jun1,ZHOU Xiao-jun2,CHEN Hong3,XIA Jun-qiang4,LI Guo-en4(1.Department of Acquired Immunodeficiency Syndrome,Donghu DistrictCenter for Disease Control and Prevention of Nanchang,Nanchang 330006,China;2.Department of Social Medicine,the School of Public Health,Nanchang University,Nanchang 330006,China;3.Department of Acquired Immunodeficiency Syndrome,Jiangxi Province Center for Disease Control and Prevention,Nanchang 330029,China;4.Department of Acquired Immunodeficiency Syndrome,Xihu District Center for DiseaseControl and Prevention of Nanchang,Nanchang 330025,China)

【机构】 南昌市东湖区疾病预防控制中心艾滋病科南昌大学公共卫生学院社会医学教研室江西省疾病预防控制中心艾滋病科南昌市西湖区疾病预防控制中心艾滋病科

【摘要】 目的探讨美沙酮维持治疗(MMT)者药物滥用因素对脱失影响与对策,为制定相应的干预对策提供依据。方法以南昌市东湖区和西湖区疾病预防控制中心2个MMT门诊就诊的MMT者719例为研究对象。采用问卷调查方法,用Cox回归方法分析MMT者药物滥用因素对脱失的影响。结果单因素Cox回归分析显示:影响MMT脱失的因素有第1次吸毒的年龄和自愿戒毒的次数。多因素Cox回归分析显示:第1次吸毒的年龄越小和自愿戒毒的次数越少者脱失率越高。结论MMT不仅是一项单纯的给服美沙酮工作,应加强对有危险脱失因素人员的管理和干预,这对于减少脱失显得尤为必要。

【Abstract】 Objective The influence of drug-buse-related factors on the loss of methadone maintenance treatment(MMT) patients have been investigated in this paper,so as to provide the basis for formulating corresponding intervention countermeasure.Methods 719 MMT cases who had participated MMT outpatient departments of Donghu and Xihu district center for disease control and prevention of Nanchang were investigated with questionnaire.Cox regression was used to analyze influence of drug-abuse-related factors on the loss of methadone maintenance treatment(MMT) patients.Results The single factor Cox regression analysis showed that The influencing factors of methadone maintenance treatment loss were the age of the first drug’s abuse and the times of voluntary drug treatment.The multivariate factor Cox regression analysis showed that the smaller age of the first drug’s abuse and the fewer the times of voluntary drug treatment,the higher the loss rate was.Conclusion MMT is not as a simple job as just giving methadone.Personnel management and intervention of the patients with the loss factors should be strengthened,and this is particularly necessary for reducing the loss.

【基金】 第四轮中国全球基金艾滋病项目应用性研究(2007OR36)
  • 【文献出处】 实用临床医学 ,Practical Clinical Medicine , 编辑部邮箱 ,2009年10期
  • 【分类号】R749.64
  • 【被引频次】2
  • 【下载频次】101
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