【摘要】 目的:探讨⁹⁹Tc^m-DTPA肾动态显像在肾移植术后监测中的图像特征和临床价值。方法:28例肾移植患者进行⁹⁹Tc^m-DTPA肾动态显像,同时测定移植肾的肾小球滤过率（GFR）和膀胱放射性计数与肾脏放射性计数比值（B/K值）,定性和定量分析肾移植术后的影像特征。结果:12例肾移植术后肾血流灌注及功能良好,GFR值为（51.5±6.3）ml/min,B/K均>3.6例急性排斥反应肾血流灌注受损程度重于功能相,GFR值为（33.4±5.7）ml/min,B/K均<1.7例慢性排斥反应肾血流灌注和功能相均同时受损,GFR值为（27.5±2.1）ml/min,B/K均<1.1例超急性排斥反应表现为放射性空白区。2例肾小管坏死肾血流灌注损伤轻于功能相。所有影像表现与临床或病理结果相吻合。结论:⁹⁹Tc^m-DTPA肾动态显像可快速且定量评价移植肾的血流和功能,早期初步鉴别排斥反应的类别且具有无创、简单、重复性强的特点。更多还原

【Abstract】 Objective:To describe the characteristics of the transplanted kidney dynamic imaging and to evaluate the clinical value of ⁹⁹Tc^m-DTPA renal dynamic imaging on allografted kidney monitoring.Methods:28 patients who underwent allogeneic kidney transplantation were examined with ⁹⁹Tc^m-DTPA dynamic imaging.Glomerular filtration rate（GFR） and bladder to kidney radioactive counting（B/K） ratio of the transplanted kidney were ac quired.The characteristics of transplanted kidney dynamic imaging were analyzed quantitatively and qualitatively. Results:The perfusion and function of 12 patients with allografted kidney were normal,GFR was（51.5±6.3）ml/ min,B/K ratio was>3.The function was superior to perfusion in 6 cases with acute rejection.GFR was（33.4±5.7） ml/min,B/K ratio was<1.The perfusion and function of 7 chronic rejection cases were impaired symmetrically. Where GFR was（27.5±2.1） ml/min,all B/K ratio was<1.There is 1 case with ultra-acute rejection showed no radioactivity.The perfusion was superior to function in 2 cases with necrosis of renal tubules.All imaging materials consistant with clinical symptoms or pathology.Conclusions:The blood flow and function of transplanted kidney can be evaluated quantitatively and rapidly by ⁹⁹Tc^m-DTPA renal dynamic imaging.⁹⁹Tc^m-DTPA dynamic imaging can identify rejection early,noninvasive,simply and repeated.更多还原