【摘要】 目的探讨双源CT灌注成像技术在颈部淋巴结病变定性诊断中的价值。资料与方法对40例颈部肿大淋巴结行CT灌注扫描,将其中34例有完整手术病理结果的病例根据其良恶性分为两组,分析良恶性淋巴结的时间密度曲线(TDC)及灌注参数的特点,比较各灌注参数的统计学差异。结果良性淋巴结组TDC以缓升型为主(87.5%),甲状腺癌转移淋巴结TDC以速升速降型为主(62.5%),淋巴瘤TDC以低平型为主(60%),其他癌(鳞癌、腺癌)转移淋巴结TDC多呈速升缓降型(62.5%);恶性淋巴结组的血流量(BF)、血容量(BV)、Patlak血容量(P-BV)、达峰时间(TTP)及强化值(EV)均高于良性组,其差异有统计学意义(P<0.05)。结论颈部良、恶性淋巴结病变及不同类型恶性淋巴结病变的CT灌注特点不同,CT灌注成像技术对颈部淋巴结病变的定性诊断有重要的应用价值。更多还原

【Abstract】 Objective To explore the value of DS-CT perfusion(CTP) imaging in differential diagnosis of benign and malignant neck lymph nodes.Materials and Methods CTP was performed in 33 patients,among them,28 cases had been certified by pathology.The patients were classified into 2 groups:benign group of 7 patients and malignant group of 21 patients.The data of perfusion parameters and TDC were recorded and analyzed statistically between 2 groups.Resu-lts The average of blood flow(BF),blood volume(BV),Time to Peak(TTP),Enhancement Value(EV),Patlak-blood volume(P-BV)of the malignant lymph nodes were higher than those of benign lymph nodes,and had statistical differences(P<0.05).The Time-Density Curve(TDC) of CT perfusion imaging could be classified into 4 types: slowly ascending curves were showed in 87.5% of benign lymph nodes,rapid ascending and rapid descending curves were presented in 62.5% of thyroid carcinoma,low level curves were showed in 60% of malignant lymphomas.Conclusion The features of the CTP are different between benign and malignant lymph nodes of neck,which are helpful for the differential diagnosis.更多还原