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母牛分枝杆菌菌苗免疫治疗结核性渗出性胸膜炎的临床观察
The clinical observation of M.vaccae vaccine immunotherapy on tuberculous exudative pleurisy
【摘要】 目的观察母牛分枝杆菌(M.vaccae)菌苗免疫治疗结核性渗出性胸膜炎(TEP)的近期远期疗效。方法TEP100例,配对随机分为M.vaccae治疗组和激素对照组,观察在全身化疗基础上M.vaccae的疗效和对免疫功能的调节作用。结果TEP经免疫治疗后近期疗效无差异,远期疗效明显高于对照组(P<0.01);M.vaccae可使CD4及CD4/CD8升高。结论M.vaccae免疫治疗TEP具有较高价值。
【Abstract】 Objective To observe the short-term and long-term curative effect of the cow mycobacterium vaccae(M.vaccae)vaccine immune treatment on tuberculous exudative pleurisy(TEP).Methods 100 cases of TEP were randomly divided into the(M.vaccae)treatment group and the hormone comparative group,and the observations were made on the curative effect of M.vaccae and the adjustment effect for the immune function on the basis of total chemo-treatment.Results After the immune treatment,the short-term curative effect of TEP allowed no group difference.But the long-term curative effect was apparently higher in the treatment group than that of the comparative group(P<0.01).M.vaccae can make CD4 and CD4/CD8 increase.Conclusion M.vaccae immune treatment on TEP is valuable.
【Key words】 M. vaccae; immunotherapy; tuberculous exudative pleurisy;
- 【文献出处】 临床肺科杂志 ,Journal of Clinical Pulmonary Medicine , 编辑部邮箱 ,2009年02期
- 【分类号】R521.7
- 【被引频次】3
- 【下载频次】33