【摘要】 目的采用心力衰竭综合超声心动图多项参数来评价左心室射血分数基本正常的心脏瓣膜病变患者的整体心功能,为临床评价心脏瓣膜病患者心功能提供一个更为全面、客观、量化的指标。方法选取心脏瓣膜病变患者56例和对照组37例,所有入选者均采用我院制定的综合超声心动图多项参数的心力衰竭超声指数进行评分,并将该评分与同期血浆脑钠素(BNP)检测结果及纽约心功能分级进行比较。结果心力衰竭超声指数在心脏瓣膜病变患者组明显高于对照组(P<0.01),且随着纽约心功能分级的升高而升高,心功能Ⅱ、Ⅲ、Ⅳ级患者的心力衰竭超声指数分别为2.38±0.92、3.51±0.93、4.35±1.22,各亚组间比较差异均有统计学意义(P<0.05),相关性分析得出心力衰竭超声指数与血浆BNP高度相关(r=0.822,P<0.05)。结论应用心力衰竭超声指数结合临床表现评价心脏瓣膜病变患者的整体心功能是可行的,可作为一个新指标值得临床推广应用。更多还原

【Abstract】 Objective To evaluate the heart function of patients with valvular disease.Using heart failure echocardiography index(HFEI),which synthesizes the multinomial parameters of echocardiography.The aim is to provide an impersonal,comprehensive and numerable criterion for appraising chronic congestive heart failure.Methods Totally 56 patients with valvular disease(valvular disease group) and 37 normal controls(control group) were involved in the study.All the subjects were graded by HFEI,which was put forward by the hospital and the multinomial parameters of echocardiography were synthesized.At the same time,the scores of HFEI were compared with the outcomes of contemporaneous brain natriuretic peptide(BNP) and the NYHA class.Results HFEI in valvular disease group was higher than that in control group(P<0.01) and increased with the growing of the NYHA functional class.The scores of patients in NYHA class Ⅱ,Ⅲ,Ⅳ were 2.38±0.92,3.51±0.93,4.35±1.22,respectively(all P<0.05).The analysis by Spearman rank correlation showed that HFEI and BNP had remarkable correlation(r=0.822,P<0.05).Conclusion It is feasible to evaluate the degree of valvular disease by HFEI with clinical symptom,and it is worth generalizing in clinic.更多还原