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半制备反相高效液相色谱法分离珍珠菜中木脂素类成分
Studies on Lignans of Lysimachia clethroide Duby by Semipreparative RP-HPLC
【摘要】 对珍珠菜(Lysimachia clethroideDuby)中的木脂素类化学成分,采用Sephadex LH-20和半制备反相高效液相色谱法联用分离化合物,从中分离并鉴定了两个化合物,通过波谱技术鉴定其化合物的结构分别是:(+)-Isolar-ic iresinol-9′-β-D-glucopyranoside(1).Urolignoside(2).化合物1和2均为首次从该属植物中分离得到.
【Abstract】 To study the chemical constituents of lignans in Lysimachia clethroide Duby.The compounds were isolated and purified by Sephadex LH-20 and Semipreparative RP-HPLC,the structures of the chemical constituents were identified by extensive spectroscopic data analysis.Two lignans were obtained and identified as:(+)-Isolariciresinol-9′-β-D-glucopyranoside(1),Urolignoside(2).Compounds 1 and 2 were isolated from this genus for the first time.
【关键词】 半制备反相高效液相色谱法;
珍珠菜;
木脂素;
【Key words】 Semipreparative RP-HPLC; lignans; Lysimachia clethroide Duby;
【Key words】 Semipreparative RP-HPLC; lignans; Lysimachia clethroide Duby;
【基金】 昆明医学院研究生创新基金资助项目(KM2008J07)
- 【文献出处】 昆明学院学报 ,Journal of Kunming University , 编辑部邮箱 ,2009年03期
- 【分类号】R284.1
- 【被引频次】10
- 【下载频次】258