【摘要】 目的探讨阿魏胶囊对高脂血症大鼠及家兔的预防作用。方法将家兔及大鼠随机分为模型组,阿魏胶囊低、中、高剂量组,辛伐他汀片组和正常对照组。正常对照组给予普通饮食,其余各组给予高脂饮食,同时给药组分别在给药4周和7周后,测定胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)等指标。结果阿魏胶囊组可降低血清TC、TG、LDL-C,升高血清HDL-C/TC比值,与模型组相比差异有统计学意义(P<0.05)。结论阿魏胶囊对高脂血症大鼠及家兔有明显预防作用。更多还原

【Abstract】 Objective:To investigate the preventive effect of Awei Capsules on hyperlipiemia in rats or rabbits.Method The rats and rabbits were randomly divided into the model group,Awei Capsules group 1,2 and 3(with low,medium and high dose of Awei Capsules respectively),Simvastatin Tablets group and normal control group.The normal control group was feed general diet and other groups were given fatty food and relevant drugs respectively.After 4 and 7 weeks the levels of total cholesterol(TC),triglyceride (TG),high-density lipoprotein-cholesterol(HDL-C) and low-density lipoprotein-cholesterol(LDL-C) were detected.Result In Awei Capsules groups the levels of TC,TG and LDL-C decreased and the ratio of HDL-C to TC increased with a statistical significance in difference between them and the model group(P<0.05).Conclusion Awei Capsules has an obvious preventive effect on hyperlipidemia in rats or rabbits.更多还原