【摘要】 目的了解佛山地区人群血清丙型肝炎病毒抗体(抗-HCV)的阳性率、丙型肝炎病毒(HCV)主要传播方式以及在普通人群中展开抗-HCV检测的意义。方法用酶联免疫吸附试验法检测2001～2007年佛山地区人群血清抗-HCV,统计每年的阳性率,观察HCV感染趋势。通过病史调查观察传播方式的变化。结果2001～2007年抗-HCV阳性率依次为0.42%、0.44%、0.45%、0.45%、0.46%、0.47%、0.48%,呈轻微上升趋势,输血感染HCV占主要比例,但总体呈下降趋势,而静脉吸毒引起的HCV感染占第2位,且呈上升趋势。结论2001～2007年佛山地区HCV感染呈每年轻微上升趋势,情况不可轻视,输血及静脉吸毒是主要传播方式,在普通人群中展开抗-HCV检测可有效地掌握人群中HCV感染情况,对丙型肝炎患者的早期发现及阻止HCV在人群中传播有重要意义。更多还原

【Abstract】 Objective To investigate the positive rate of serum anti-HCV and the main mode of transmission of HCV in Foshan region,and evaluate the clinical significance of anti-HCV detection in common people.Methods Enzyme linked immunosorbent assay (ELISA) was applied to detecting serum anti-HCV in people in Foshan region from 2001 to 2007; the annual positive rate was recorded,and the HCV infection tendency was observed.The variability of infection way was investigated by investigating the case history.Results The positive rates of anti-HCV from 2001 to 2007 were 0.42%,0.44%,0.45%,0.45%,0.46%,0.47% and 0.48% respectively,displaying a slightly rising trend.HCV infection due to blood transfusion was dominant,displaying a declining tendency; followed by that due to venous narcotic taking,displaying a slightly rising trend.Conclusion There is a slightly ascendent tendency in HCV infection in Foshan region from 2001 to 2007 and the situation shouldn’t be despised.Blood transfusion and venous drug taking are the main infection ways.It plays an important role to availably grasp the situation of HCV infection by detecting serum anti-HCV in common people in early diagnosis of hepatitis C and timely prevention of HCV transmission in crowd.更多还原