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脑血栓形成患者脂蛋白(α)与糖尿病的关系

Relationship between Lipoprotein (α) and Cerebral Thrombosis

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【作者】 杨芳; 陈兵;

【Author】 Ysng Fang1,Chen Bing2 (1.Department of NO.1 Internal Medicine,Wulian County People’s Hospital Shandong Provtnce,Wulian 262300,China;2.Department of Neurology,Second Affiliated Hospital of PLA General Hospital,Beijing 100091,China)

【机构】 山东省五莲县人民医院内一科; 解放军总医院第二附属医院神经内科;

【摘要】 目的探讨脑血栓形成患者脂蛋白(α)[Lp(α)]与糖尿病之间的关系。方法采用ELISA双抗体夹心法分别检测糖尿病与非糖尿病性脑血栓形成患者的血清Lp(α),并分别比较两者之间以及对照组Lp(α)水平。结果脑血栓形成患者合并糖尿病组与对照组比较Lp(α)血浆浓度明显增高,差异有显著统计学意义(P<0.01);脑血栓形成患者中合并糖尿病组与无糖尿病组Lp(α)差异也有统计学意义(P<0.05)。结论Lp(α)是缺血性脑卒中的一个危险因素,脑血栓形成患者中Lp(α)与糖尿病有一定的关联性。

【Abstract】 Objective To investigate the exact relation between Lp(α) value of cerebral thrombosis patients and diabetes mellitus. Methods ELISA were used to test serum Lp(α) value of diabetes mellitus patients in cerebral thrombosis and pure cerebral thrombosis patients respectively,and compare the Lp(α)level of these two sample test groups. Results Compare with the plasma level of lipoprotein(α)of pure cerebral thrombosis patients,the chroma of diabetes mellitus patients in cerebral thrombosis is remarkable increased. These difference remained significantly higher (P<0.01),the difference of plasma level of lipoprotein(α) for pure cerebral thrombosis patients and diabetes mellitusin cerebral thrombosis also remained significantly higher(P<0.05).Conclusion Lp(α) is one risk factor of ischemic cerebral stroke,Lp(α) value of cerebral thrombosis patients were correlated with diabetes mellitus.

  • 【文献出处】 临床军医杂志 ,Clinical Journal of Medical Officers , 编辑部邮箱 ,2009年05期
  • 【分类号】R743.32;R587.1
  • 【被引频次】7
  • 【下载频次】63
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