【摘要】 目的探讨甲状腺相关眼病(TAO)不同严重度分级的MRI影像变化。方法64例TAO患者采用NOSPECS标准评分及磁共振(MRI)行眼眶扫描,对MRI诊断及NOSPECS评分进行比较。结果NOSPECS2级1例,MRI表现为眼眶软组织影增厚;3级13例,其中8例MRI显示眼外肌增厚;4级45例,MRI表现为眼外肌增粗,以肌腹部增厚为主;5级3例,MRI对角膜的显示欠满意;6级2例,MRI表现为视神经轴受压、行程改变。MRI对眼外肌受累的显示率明显高于NOSPECS评分(P<0.05)。结论MRI显示TAO不同严重度分级的病理改变,增加了早期不典型4级TAO的发现率,克服NOSPECS评分滞后的缺陷。更多还原

【Abstract】 Objective To describe MRI manifestations of thyroid associated ophthalmopathy(TAO)in every clinical grade.Methods Sixty-four TAO cases were collected.Severity of TAO was evaluated by Werner NOSPECS Scores.All the cases were examined by Siemens Magnetism Vision Plus 1.5T.Scanning plan consisted spin echo sequence,STIR(Short TI Inversion recovery)sequence,SE dual-echo sequence and SE dual-echo sequence with dispose suppression.Results NOSPECS Scores graded 64 TAOs by:1 case in Grade 2,MRI showed orbital soft tissue swelled;13 cases in Grade 3,EOM(Extraocular muscle)was enlarged in 8 cases;45 cases were in Grade 4,EOM abdomen was observed shapely enlargement;3 cases were in Grade 5,but it was difficult for MRI to show cornea;2 cases were in Grade 6.Optic neural axis was suppressed and translocated in MRI pictures.MRI had a higher detection rate in EOM than NOSPECS Scores(P<0.05).Conclusion MRI demonstrates the pathological changes in different grading TAO and detects more early,untypical grade 4 cases,therefore overcomes the shortcoming of NOSPECS Scores.更多还原