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马齿苋生物碱对A-549细胞的抑制作用
Experimental study of alkaloid from Portulaca oleracea L.on the inhibition of A-549 cell
【摘要】 目的:研究了马齿苋生物碱对体外培养人肺腺癌细胞株(A549cell)的增值抑制。方法:MTT比色法间接测定生物碱对A-549cell增值的影响。结果:马齿苋生物碱具有抑制体外培养A-549cell增殖作用,并随药物浓度增加和作用时间的增长其效应增强。结论:马齿苋生物碱具有抑制肿瘤细胞生长的作用,可望开发成为抗癌的功能性食品或药物。
【Abstract】 OBJECTIVE:To study the inhibition of alkaloid from Portulaca oleracea L.on A-549 cell in vitro.METHODS:Inhibition of proliferation was measured by MTT assay.RESULTS:alkaloid from Portulaca oleracea L.can inhibit the growth of the tumor and the effect is improved when the concentration is increasing.CONCLUSION:alkaloid from Portulaca oleracea L.can inhibit the growth of the tumor and it is promising that it may be an against cancer functional foods and/or drug.
【关键词】 马齿苋;
生物碱;
人肺腺癌细胞株(A549cell);
细胞毒效应;
【Key words】 Portulaca oleracea L.; alkaloid; A-549 cell; cytotoxicity;
【Key words】 Portulaca oleracea L.; alkaloid; A-549 cell; cytotoxicity;
- 【文献出处】 江西食品工业 ,Jiangxi Food Industry , 编辑部邮箱 ,2009年01期
- 【分类号】R734.2
- 【被引频次】11
- 【下载频次】364