【摘要】 目的观察自然夜间多导睡眠图(PSG)对首发抑郁症患者的诊断价值。方法应用日本1518K多导睡眠生理仪,采用眼电图和下颌肌电图及脑电图等技术,对24例首发抑郁症患者的多导睡眠图(PSG)进行整夜监测,并与21名正常受试者对照。结果首发抑郁症患者组PSG主要指标表现为REM睡眠潜伏期(RL)前移[正常组(81±11)min,首发抑郁症患者组(62±19)min,P<0.01];睡眠维持率(SMT)下降[正常组(98±5)%,首发抑郁症患者组(87±8)%,P<0.01],第二阶段睡眠降低[正常组(57±5)%,首发抑郁症患者组(43±12)%,P<0.01]及REM3个睡眠参数有改变。结论REM睡眠潜伏期前移是首发抑郁症的特点。更多还原

【Abstract】 Objective:To estimate the diagnostic value of.spontaneous evening sleep polysomnography(PSG) in first episode depression.Methods:The whole night PSG were recorded from 24 patients with first episode depression.and 21 normal subjects,using Neurofax-1518K(Nihon Kohden) sleep instrument.Results:Compared with normal subjects,first episode depression patients showed shorted REM latency(NC:81±11,first episode depression group:62±19,P<0.01),reduced sleep maintenance(NC:98±5%,first episode depression group:87±8%,P<0.01),decreased stage 2 sleep(NC:57±5%,first episode depression group:43±12%,P<0.01).Conclusion:Patients with first episode depression exhibit abnormality in sleep continuity,sleep frame,and REM.更多还原