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解毒活血方案对颈动脉粥样硬化血流动力学影响的探讨

Hemodynamic effects of toxin-resolving and blood-activating in carotid atherosclerosis

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【作者】 田庆新李新爱郭庆河刘鹏殷镜海

【Author】 TIAN Qingxin,LI Xin’ai,GUO Qinghe,et al.The Affiliated Hospital of Shandong University of TCM,Jinan,250011,China.

【机构】 山东中医药大学附属医院山东省济南卫生学校

【摘要】 目的:观察解毒活血配伍方案对颈动脉粥样硬化血流动力学的影响。方法:入选颈动脉粥样硬化患者120例,随机分为4组,即A组(解毒组)、B组(活血组)、C组(解毒活血配伍组)、D组(洛伐他汀对照组),疗程6月。采用高分辨力超声技术观察治疗前后颈动脉血流动力学改变。结果:解毒活血配伍组提高PSV、EDV、PI,降低RI的疗效优于单纯解毒组、活血组及洛伐他汀组,可显著改善颈动脉血流动力学,从而稳定颈动脉粥样硬化斑块。结论:解毒活血配伍具有稳定颈动脉粥样硬化斑块的作用,疗效优于单纯解毒、活血及洛伐他汀组。

【Abstract】 Objective: To observe the hemodynamic effects of toxin-resolving and blood-activating in carotid atherosclerosis.Methods: One hundred and twenty patients of carotid atherosclerosis were divided into 4 groups randomly: A group(toxin-resolving group),B group(blood-activating group),C group(toxin-resolving and blood-activating group) and D group(lovastatin group).The course of treatment was six months.Hemodynamic changes were observed by high resolution ultrasound.Results: Compared to other groups,EDV,Vm and PI were significantly increased while RI was significantly decreased in C group,which showed the principle of toxin-resolving and blood-activating could improve hemodynamic indexes and stabilize carotid atherosclerotic plaque.Conclusion: The principle of toxin-resolving and blood-activating can stabilize the carotid atherosclerotic plaque,which are superior to toxin-resolving or blood-activating.

【基金】 山东省中医管理局2005~2006年度科技基金课题(编号:2005-143)
  • 【文献出处】 中国中西医结合影像学杂志 ,Chinese Imaging Journal of Integrated Traditional and Western Medicine , 编辑部邮箱 ,2009年03期
  • 【分类号】R277.7
  • 【被引频次】7
  • 【下载频次】26
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