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Zwitterionic phosphorylcholine-protected water-soluble Ag nanoparticles

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【Author】 JIN Qiao,LIU XiangSheng,XU JianPing,JI Jian & SHEN JiaCong Key Laboratory of Macromolecule Synthesis and Functionalization of Ministry of Education,Department of Polymer Science,Zhejiang University,Hangzhou 310027,China

【摘要】 The water-soluble Ag nanoparticles capped with novel zwitterionic thioalkylated phosphorylcholine were synthesized.The Ag nanoparticles showed remarkable stability in saline media with salt concen-trations as high as 2.0 mol/L and plasma using UV-vis absorption spectroscopy.Similarly,compared with tiopronin and citrate-protected Ag nanoparticles,the zwitterionic phosphorylcholine Ag nanopar-ticles did not precipitate out of solution when charged polyelectrolytes or biopolymers were added.The zwitterionic phosphorylcholine might be a better ligand for stabilizing metal nanoparticles.

【Abstract】 The water-soluble Ag nanoparticles capped with novel zwitterionic thioalkylated phosphorylcholine were synthesized.The Ag nanoparticles showed remarkable stability in saline media with salt concen-trations as high as 2.0 mol/L and plasma using UV-vis absorption spectroscopy.Similarly,compared with tiopronin and citrate-protected Ag nanoparticles,the zwitterionic phosphorylcholine Ag nanopar-ticles did not precipitate out of solution when charged polyelectrolytes or biopolymers were added.The zwitterionic phosphorylcholine might be a better ligand for stabilizing metal nanoparticles.

【基金】 Supported by the National Natural Science Foundation of China (Grant Nos. 20774082 and 50703036);National High Technology Research and Development Program of China (Grant Nos. 2006AA03Z329 and 2006AA032444);Science and Technology Projects of Zhejiang Province (Grant No. 2007C24G2010020)
  • 【文献出处】 Science in China(Series B:Chemistry) ,中国科学(B辑:化学)(英文版) , 编辑部邮箱 ,2009年01期
  • 【分类号】O614.122
  • 【被引频次】3
  • 【下载频次】31
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