【摘要】 目的探讨鄂尔多斯高原碱湖钝顶螺旋藻S₁和Chad湖钝顶螺旋藻S₂对小鼠非特异性免疫功能的差异。方法以健康昆明小鼠（20±2g）为对象,随机分为对照组和实验组,后者分别采用S₁和S₂的藻粉配制浓度分成高（1.25×10²g/1）、中（1.25×10¹g/1）、低（1.25g/1）3个剂量组,灌胃1ml/只,1次/d×21d,检测免疫指标。结果S₁和S₂实验组体内淋巴细胞转化率和腹腔巨噬细胞吞噬率均高于对照组（P<0.01和P<0.05）,其中S₁中剂量组和S₂高剂量组的效果最佳。结论S₁和S₂均能够明显的增强小鼠非特异性免疫功能,达到最佳效果所需剂量,前者仅是后者的1/10;在相同剂量下,S₁比S₂的作用更明显。更多还原

【Abstract】 objective The study focuses on compare the nonspeciflc immune function between Spirulina platensis from alkaline lakes in Erdos Plateau S₁ and Chad lakes S₂ in mouse.Methods The object for the healthy Kunming mouse（20±2g）were individed randomly into normal control and experiment group.The latter were used the S₁ and S₂ powder in high-dose（1.25×10²g/l）,mid-dose（1.25×10¹g/l）and low-dose（1.25g/l）.Every mouse was given 1ml/d×21d, immunolgical indexes were detected.Results The lymphocyte transformation rate and the phagocytic rate of macrophage were significant to control group in every doses group either S₁ or S₂（P<0.01 and P<0.05）,the best were mid-does groups in S₁ and high groups in S₂.Conclusion The experiment results indicated that the S₁ and S₂ can obviously enhance the nonspecific immunity in mouse,the dose achieving to the best effect in S₁ is 1/10 of the S₂;in same does, S₁ have obviously effect than S₂.更多还原