淋巴瘤患者血浆D—二聚体和FDP检测的临床意义

【摘要】 目的探讨淋巴瘤患者治疗前后血浆D-二聚体(D-dimer,D-D)及血浆纤维蛋白原降解产物(FDP)的变化,并观察二者水平变化与疗效及预后的关系。方法对确诊为45例不同组别的淋巴瘤患者和30例健康体检者进行血浆FDP和D-D水平检测。结果初治组较对照组血浆FDP和D-D阳性率明显升高(P<0.01),完全缓解组(CR)较未达完全缓解组其阳性率下降有显著学差异。结论淋巴溜患者血浆FDP和D-D含量变化可能对淋巴瘤患者疗效及预后有一定的预测作用。更多还原

【Abstract】 Objection To investigate the relationship between plasma D-dimer and FDP and lymphoma patient’ s prognosis.Methods The lymphoma patients plasma levels of D-dimer and FDP were measured by enzyme linked-immunoadsorbent assay(ELISA) in forty five patients.We compared the lymphoma patients’ D-dimer and FDP with healthy men as control group,parameters with different groups divided by the level of blood lymphoma with treatment affection.We also analyzed the correlationship between D-dimer and FDP and lymphoma prognosis in lymphoma patients.Results The levels of plasma D-dimer and FDP are remarkable higher in patients than the control group(P<0.01).The levels of plasma D-dimer and FDP is higher in the group of complete remission(CR) than in the group of non-CR(P<0.01).Conclusion The change in levels of plasma D-dimer and FDP play an important predictive value in lymphoma prognosis.更多还原