【摘要】 以3,4-二甲基苯胺为原料,经重氮化和溴代合成标题化合物。溴代反应以液溴为溴化剂,操作简便、收率较高。考察了原料配比、反应时间和温度对反应的影响,优化出一条较为理想的工艺条件。所得产品结构通过GC-MS、1HNMR进行了表征。更多还原

【Abstract】 1,2-Bis(bromomethyl)-4-fluorobenzene was synthesized from 3,4-dimethylbenzenamine via reactions involving diazotization and bromination.Radical bromination of 1,2-dimethyl-4-fluorobenzene was carried out using bromine to prepare 1,2-bis(bromomethyl)-4-fluorobenzene.Some factors affecting the reaction,such as the raw material rate,the reaction time and the reaction temperature,were also discussed.The selection and development of the reasonable and feasible synthetic conditions were introduced.The structures of the products were characterized by GC-MS,and 1HNMR techniques.更多还原