【摘要】 目的:观察水通道蛋白-4(AQP4)在大鼠眼虹膜睫状体及视网膜组织中的分布。方法:取6只正常Wist-ar大鼠眼组织切片,行免疫组织化学染色,光镜下观察AQP4的分布。结果:睫状体上皮细胞AQP4呈阳性表达,睫状体及虹膜内血管内皮细胞均有AQP4阳性表达,视网膜内核层及神经节细胞层也可见AQP4阳性表达。结论:AQP4在大鼠睫状体上皮细胞及视网膜内核层、神经节细胞层分布,可能参与房水调节及神经节水代谢功能调节。更多还原

【Abstract】 Aim:To examine the distribution of aquaporin-4 (AQP4) in iris ciliary and retina of rat.Methods:Expression of AQP4 in the eye tissue of normal Wistar rat was investigated by using immunohistochemical staining.Results:Immunoreactive AQP4 was expressed in ciliary epithelial cells,vascular endothelial cells of iris and ciliary,inner nuclear layer and ganglion cells layer of retina.Conclusion:AQP4 is expressed in ciliary epithelial cells,inner nuclear layer and ganglion cells layer of retina,which may play important roles in regulation of aqueous fluid secretion and normal function of ganglion cells of retina.更多还原