【Abstract】 [Objective] To detect the mRNA of muscle insulin-like growth factorⅠ(IGF-Ⅰ) in the early development of Kazak sheep and Xinjiang fine-wool sheep,so as to provide information for the research about the early growth and development of sheep.[Method] With real-time quantitative PCR,the muscle IGF-Ⅰ mRNA level was separately detected in two varieties of sheep at 2,30,60,90 and 120 days old.Then the data was analyzed with SPSS software.[Result] The IGF-Ⅰ mRNA in sheep muscle first increased and then decreased with ages,peaking at 30 days old in Kazak sheep and at 60 days old in Xinjiang fine-wool sheep.The IGF-Ⅰ expression level of Kazak sheep had no significant difference with Xinjiang fine-wool sheep at 2 or 90 days old(P>0.05),but was lower than that of the latter with extremely significant difference(P<0.01) from 30 to 60 days old.[Conclusion] The male Kazak sheep and Xinjiang fine-wool sheep have similar model of developmental changes of muscular IGF-Ⅰ mRNA,but the expression level is different between these two species.更多还原