【摘要】 目的:探讨2型糖尿病患者血清铁蛋白检测的临床意义。方法:对100例2型糖尿病患者以及75例健康体检者分别测定空腹血糖(FBG)、餐后2h血糖(PBG)、空腹胰岛素(FINS)、血清铁蛋白(SF)和糖化血红蛋白(HbA1C)。结果:实验组与对照组相比,具有较高的FBG、PBG、HbA1C、SF,差异具有显著性(P<0.01);胰岛素抵抗指数(HOMA-IR)明显升高(P<0.01);实验组的FINS高于对照组,差异有显著性(P<0.05)。结论:2型糖尿病患者体内铁贮备增多;铁超负荷导致胰岛素抵抗;测定血清铁蛋白可以预测糖尿病代谢控制程度。更多还原

【Abstract】 Objective:To explore clinical significance of the level of serum ferritin in patients with type 2 diabetes.Method: A total of 100 patients with type 2 diabetes and 75 healthy subjects were enrolled in this study.All subjects were evaluated the levels of fasting and postprandial glucose,serum ferritin and hemoglobin A1c(HbA1c),Insulin resistance was determined by using the homeostasis model assessment.Result:The levels of serum fasting or postprandial glucose or HbA1c or fasting insulin or the index of insulin resistance in patients with type 2 diabetes were significantly higher than those in healthy subjects(P<0.05),and the concentration of serum ferritin was notable high in patients with diabetes.Conclusion:The iron storage was overload in patients with type 2 diabetes,and the overload iron storage may lead to the development of insulin resistance.The level of serum ferritin may be a marker to predict the metabolic conditions for the diabetic patients.更多还原