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肾移植术后早期排异的处理

Management of Early Postoperative Renal Transplant Rejection

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【作者】 李慎谦王鹏举夏青柳东夫

【Author】 LI Shen-qian,et al(The Affiliated Hospital of Medical College of Qingdao University,Shandong Qingdao 266011,China)

【机构】 青岛大学医学院附属医院泌尿外科青岛大学医学第二院附属医院山东省烟台市毓璜顶医院泌尿外科

【摘要】 目的:探讨肾移植早期急性排斥反应的诊断及治疗方法。方法:肾移植98例病例中对18例肾移植术后发生早期(1个月内)急性排斥反应的诊断及治疗进行分析。结果:18例早期急性排斥反应经治疗后均成功。结论:早期急性排斥反应是同种异体肾移植术后最重要问题之一,甲强龙能很好的使术后早期急性排斥反应逆转。对加强龙反应差者,及时配合应用FK506,抗CD3可使术后早期急性排斥反应逆转。成功的关键是早期诊断,早期治疗。

【Abstract】 Objective: To investigate the diagnosis and treatment of early acute rejection after renal transplantation.Method: The diagnosis and treatment of 18 in 98 patients who suffered from acute rejection within 1 month after renal transplantation were analyzed.Result: All the 18 patients received successful treatment.Conclusion: The early acute rejection after renal transplantation is one of the most important issue.Prednisolone can make a good reversal.To poor-response cases to the prednisolone,the application of FK506,anti-CD3 in time can well reverse the early postoperative acute rejection.The key step to success is early diagnosis and treatment.

【关键词】 肾移植急性排异反应
【Key words】 Renal transplantationAcute rejection
  • 【分类号】R699.2
  • 【下载频次】116
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