【摘要】 目的比较中低位直肠癌实施Dixon手术中,使用双吻合器吻合与人工吻合的疗效。方法回顾性分析接受Dixon手术治疗的中低位直肠癌患者84例,按照吻合技术,分为双吻合器组56例和人工吻合组28例;比较2组的手术时间、术中失血量及术后并发症发生率;随访3年,比较肿瘤复发率及生存率。结果 2组肿瘤分期差异无统计学意义(P>0.05)。双吻合器组手术时间为(102.7±11.2)min,明显少于人工吻合组(167.0±12.7)min(P<0.01);术中失血量也少于人工吻合组[(180.4±45.4)mL vs(327.5±57.0)mL,P<0.01]。双吻合器组术后并发症发生率为10.7%(6/56),人工吻合组为1 7.8%(5/28),差异无统计学意义(P>0.05)。双吻合器组3年肿瘤复发率为5.5%,3年生存率为96.4%;人工吻合组分别为8%、96.0%;2组相比差异均无统计学意义(P>0.05)。结论与人工吻合相比,双吻合器可明显缩短手术时间、减少术中失血量;但是不能降低术后并发症发生率、3年肿瘤复发率,不能提高3年生存率。更多还原

【Abstract】 Objective To compare the result of dis-stapler and manual anastomosis in Dixon operation of midst-low rectal carcinoma.Methods According to anastomosis technique,the midstlow rectal carcinoma patients receiving Dixon operation were divided into two groups:dis-staple group and manual anastomosis group.The clinical data were analyzed to compare operation time, blood loss,post-operation complications.They were followed up for 3 years to compare 3-year tumor recurrence and survival.Results There were 84 patients enrolled in the study,58 patients in dis-stapler group,28 patients in manual anastomosis group.There was no significant difference in tumor staging between the two groups.The operation time of dis-stapler group was(102.7± 11.2)minutes,which was significantly superior to manual group [(167.0±12.7)min,P= 0.000];its blood loss was less than that in manual anastomosis group [(180.4±45.4)mL vs (327.5±57.0)mL,P=0.000];but there was no significant difference in post-operation complications between dis-stapler group and manual anastomosis group(10.7% vs 17.8%,P= 0.360).In dis-stapler group,3-year recurrence rate was 5.5%,3-year survival was 96.4%.They are respectively 8%,96% in manual anastomosis group,but there was no statistical significance, P-value was 0.728、0.992,respectively.Conclusion Compared with manual anastomosis,dis- stapler anastomosis could reduce operation time and blood loss,but it can not improve postoperative complications,3-year recurrence or 3-year survival rate.更多还原