【摘要】 采用接触、腹腔注射及口服3种致毒方式,对吉富罗非鱼(GIFT Oreochromis niloticus)进行三聚氰胺的急性毒性研究.口服急性毒性实验中,在饲料中添加不同浓度的三聚氰胺,进行21 d的吉富罗非鱼摄食养殖实验,实验鱼初体重为(55.00±0.05)g.实验结果表明:三聚氰胺溶解度较低,在接触实验中其水溶液没有表现出毒性,96LC50>3500 mg/L;而在腹腔注射致毒方式下,三聚氰胺对吉富罗非鱼的半致死剂量LD50=1311.90 mg/kg;LD5095%可信限为1169.06~1472.21 mg/kg;在21 d口服急性毒性实验中,添加三聚氰胺后不同程度地降低了吉富罗非鱼的摄食率和特定生长率,但对存活率和饲料系数均无显著影响.三聚氰胺对吉富罗非鱼21 d的最大未观察到有害作用剂量(no-observed-adverse-effect-level,NOAEL)为31.00 mg/(kg.d).更多还原

【Abstract】 In this study,the acute toxicity experiments(including touching test,injection test and oral test) were conducted on tilapia(GIFT Oreochromis niloticus) to investigate the effects of melamine on tilapia.Results showed,the solubility of melamine was low and the 96 h LC50>3 500 mg/L at 27 ℃;the LD50 of tilapia in injection test was 1 311.90 mg/kg,and the confidence limitation of LD50 95 % was 1 169.06～1 472.21 mg/kg;in oral test,21 d NOAEL(no-observed-adverse-effect-level) for melamine in tilapia was 31.00 mg/(kg·d).更多还原