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β-胡萝卜素口服液的稳定性研究
Studies on stability of β-carotene oral liquid
【摘要】 目的考察β-胡萝卜素口服液的稳定性影响因素及增加稳定性的方法。方法采用单因素分析法考察光线、空气(O2)、温度、金属离子、pH值等的影响及筛选增加稳定性的方案。结果各因素的影响程度:温度>光照>O2>金属离子>pH值;加入0.05%的维生素E可增加本品的稳定性。结论本品不稳定,在生产和储存过程中要低温、避光、避氧及加入抗氧剂。
【Abstract】 OBJECTIVE To investigate the factors which influence the stability of β-Carotene oral liquid and how to increase the stability.METHODS The single-factor analysis was used to study the effects of light,O2,temperature、metalion,pH value and screen the methods to increase the stability.RESULTS The effect degree of various factors:temperature>light>O2>metalion>pH value;add 0.05% of vitaminE can increase the stability of β-Carotene oral liquid.CONCLUSION β-Carotene oral liquid is unstable,which should be under low temperature,avoid light and O2,add oxidation-resistant during the process of production and storage.
- 【文献出处】 海峡药学 ,Strait Pharmaceutical Journal , 编辑部邮箱 ,2009年08期
- 【分类号】R151
- 【被引频次】4
- 【下载频次】232