【摘要】 目的探讨上呼吸道感染儿童鼻部致病菌的携带状况及预防性使用抗菌素在防止继发性细菌性呼吸道感染中的作用。方法将因上呼吸道感染而就诊的563例患儿随机分为两组,一组加用抗菌素治疗,一组仅对症处理。于鼻内窥镜下取中鼻道附近的粘液标本做细菌培养,并查血常规及C-反应蛋白,3d后复查血常规及C反应蛋白,以血白细胞升高及C反应蛋白升高做为判定继发细菌感染的标准。结果鼻内窥镜拭子细菌培养阳性的患儿共275例(48.85%),阴性的患儿共288例(51.15%)。鼻拭子细菌培养、治疗措施与C反应蛋白结果均有明显的相关性,三者的相互关系亦有统计学意义。结论儿童鼻部存在致病菌时,呼吸道感染容易发展为细菌性感染,预防性使用抗菌素具有临床意义。更多还原

【Abstract】 Objective To study the distribution of pathogenic bacteria in children’s nasal middle meatus with acute upper respiratory infection and the prophylactic application with antibiotics. MethodsNasal middle meatal bacterial culture was taken with endoscope. Blood differential leukocyte count and C reactive protein were studied. After three days, blood differential leukocyte count and C reactive protein were repeated. The leucocyte and C reactive protein were regarded as the standard of bacteroidal infection. Results275 cases had potentially pathogenic bacteria in the nasal middle meatus. The dependability between bacterial culture, treatment and C reactive protein was conspicuous. ConclusionWhen children have potentially pathogenic bacteria in the nasal middle meatus, respiratory infection can complicate bacteroidal infection and the antibiotic can be used.更多还原