【摘要】 目的:探讨运动后踝臂指数(postexercise ankle-brachial index,postexercise ABI)对下肢动脉疾病(lower extremity arterial disease,LEAD)的诊断阈值和诊断价值。方法:收集本院心内科119例患者进行下肢动脉CTA检测、静息ABI和运动后ABI检测,根据影像学结果,将双下肢任一血管管腔直径狭窄≥50%为LEAD组,管腔直径狭窄<50%为非LEAD组。根据下肢动脉狭窄率与静息ABI和运动后ABI的关系绘制受试者工作特征曲线(receiver operator characteristic curve,ROC curve),比较两者的曲线下面积和诊断阈值。结果:运功后ABI曲线下面积大于静息ABI的曲线下面积(0.988比0.948,P<0.01),且敏感性和特异性均高于静息ABI。结论:运动后ABI在LEAD的筛检过程中比静息ABI更具诊断意义。更多还原

【Abstract】 Objective:To explore the test threshold and diagnostic value of postexercise ankle-brachial index (postexercise ABI) for lower extremity arterial disease(LEAD).Methods:119 patients registered to Department of Cardiology in our hospital were enrolled.All the patients underwent CT angiography of lower limbs,resting and postexercise ABI measurement.According to the results of CTA,patients with≥50%lumen stenosis of any blood vessel in any one of lower limbs were allocated to the LEAD group,and those with<50%lumen stenosis were allocated to the non-LEAD group.Based on the relation between percentage stenosis and resting/post-exercise ABI,a receiver operator characteristic curve(ROC curve) was generated in order to compare the area under curve and test threshold.Results: The area under curve for postexercise ABI was larger than that for resting ABI(0.988 vs 0.948,P<0.01 ),also with higher sensitivity and specificity.Conclusion:Postexercise ABI was much more efficient than resting ABI in diagnosis of LEAD.更多还原