【摘要】 目的:探讨实验兔膝关节软骨的高场强MRI正常表现以及成像的最佳序列及参数。方法:应用飞利浦Intera 1.5T超导型磁共振扫描仪,分别采用PDW/SPAIR/D,T2W₃D_FFE及3D_WATSc序列对6只实验兔的膝关节行磁共振成像,观察不同序列关节软骨的信号特点,比较各序列的软骨信噪比（signal to noiseration,SNR）及软骨/软骨下骨对比噪声比CNR（contrast to noise ratio,CNR）。结果:兔膝关节软骨在三个序列中均表现为单层均匀的中等或高信号带;PDW/SPAIR/D、T2W₃D_FFE及3D_WATSc各序列的软骨SNR差异无显著性（P=3.840）,而软骨/软骨下骨CNR差异有显著性（P=0.045）;3D_WATSc序列的软骨/软骨下骨CNR高于PDW/SPAIR/D序列及T2W₃D_FFE序列（P<0.05）,而PDW/SPAIR/D序列和T2W₃D_FFE序列间的软骨/软骨下骨CNR差异无显著性（P>0.05）。结论:高场强磁共振下,兔膝关节软骨表现为单层均一信号,三维扰相梯度回波结合水激励技术即3D_WATSc序列,可能是观察实验兔关节软骨的最佳成像序列。更多还原

【Abstract】 Objective:To study the high field MRI appearances of normal rabbit knee articular cartilage,and evaluate the optimal sequences and parameters for imaging.Methods:a 1.5T Philip lntera MR system was used in the study,6 experimental rabbits underwent knee MRI with PDW/SPAIR/D,T2W₃D_FFE and 3D_WATSc sequences consecutively,the appearances of articular cartilage were reviewed,the cartilage signal to noise ration（SNR） and cartilage/subchondral bone contrast to noise ratio（CNR） of all MRI sequences were compared.Results:The rabbit knee articular cartilage presents as a homogeneous layer of intermediate or hyper intense signal in all 3 sequences. There was no significant difference of cartilage SNRs among PDW/SPAIR/D,T2W₃D_FFE and 3D_WATSc（P= 3.840）,but there was significant difference of artilage/subchondoral bone CNR among 3 sequences（P=0.045）. Furthermore,the CNR of 3D_WATSc was higher than those of PDW/SPAIR/D and T2W₃D_FFE（P<0.05）,while there was no difference of CNRs between PDW/SPAIR/D and T2W₃D_FFE（P>0.05）.Conclusion:The articular cartilage of rabbit knee,imaged by a high filed MRI,was demonstrated as a single layer band with homogeneous signal. 3D-spoiled gradient echo with water excitation technique,viz.a 3D_WATSc sequence,was the optimal sequence for articular cartilage imaging.更多还原