【摘要】 目的探讨靶血管栓塞后手术治疗复发性骶骨脊索瘤的临床疗效。方法对1993～2008年间36例骶骨脊索瘤患者进行回顾性分析,将27例初发患者列为初发组,外院初次手术后复发来我院9例列为复发组。所有患者均采用靶血管栓塞后行后路手术。统计学分析两组病例术中出血量、输血量、术后引流量、伤口并发症、术后二便功能和复发情况。结果两组患者平均出血量、平均输血量、术后引流量差异无统计学意义,P>0.05。平均随访68个月,复发组术后大小便功能障碍较初发组多(P<0.05)。初发组复发10例,复发组再次复发7例,差异有统计学意义(P<0.05)。结论选择性靶血管栓塞可有效地减少术中出血,对于复发性骶骨脊索瘤仍是安全有效的方法。复发性骶骨脊索瘤术后大小便功能恢复较初发患者差,并且较初发患者更易复发。更多还原

【Abstract】 Objective To investigate the curative effect of surgical treatment for recurring sacral chordoma after target vessel embolization.Methods Thirty-six patients with sacral chordomas which were from 1993 to 2008 were retrospectively analysed.All patients were divided into 2 groups:primary group(n=27),and recurring group(n=9). All patients underwent surgery with a posterior approach after target arterial embolization.Blood loss,blood transfusion, blood drain,wound complication,post-operative function of the bladder and rectum,and the recurrence in both groups were analyzed.Results There was no significant difference in blood loss,blood transfusion,blood drain between two groups(P>0.05).The average follow-up was 68 months.The post-operative function of bladder and rectum of the recurring group was worse than that of the primary group(P<0.05).There were ten patients had relapse in primary group, and seven patients in recurring group.The difference was significant(P<0.05).Conclusions Target arterial embolization can decrease the blood loss and increase the possibility to remove the sacral chordoma completely.So it is a safe and effective method for recurring sacral chordoma.The post-operative function of bladder and rectum of recurring patients is worse than that of primary patients,and the recurrence rate is higher.更多还原