【摘要】 为了探讨超声介导不同浓度微泡造影剂(MBCA)-声诺维(SonoVue)对人脐静脉血管内皮细胞(HUVEC)凋亡及活性的影响。应用Annexin-v-FITC和PI双标记细胞凋亡检测试剂盒检测不同浓度SonoVue对HUVEC凋亡及活性的影响。结果在超声介导下,随着SonoVue浓度的增加,活细胞数呈减少趋势,早期凋亡、晚期凋亡和坏死细胞数呈增加趋势。超声介导下(超声能量一定时)不同浓度SonoVue对HUVEC有着不同的影响。更多还原

【Abstract】 This is a study of the effects of ultrasond-mediated microbuble contrast agent(MBCA)-SonoVue in different concentrations on apoptosis and activity of Human umbilical vein endothelial cell(HUVEC).HUVEC apoptosis and activity were detected with Annexin-v-FITC and PI paired labeled cell apoptosis detect agent kit in different concentrations Ultrasound-mediated SonoVue.with Ultrasound-mediated SonoVue,the higher concentration,the less quantity of viable cells and the more quantity of cell apoptosis and death.Ultrasond-mediated SonoVue of different concentrations exerts different effects on HUVEC.更多还原