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一株H5N1亚型高致病力禽流感病毒人工感染鸭的18项血液生化指标测定

Eighteen Blood Biochemical Indexes Assay of Ducks Experimentally Infected with a Highly Pathogenic Avian Influenza Virus,A/duck/Guangdong/220/2004(H5N1)

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【作者】 李玉谷崔聪颖周泉鹤叶远兰马勇江张媛李楚宣

【Author】 LI Yu-gu,CUI Cong-ying,ZHOU Quan-he,YE Yuan-lan,MA Yong-jiang,ZHANG Yuan,LI Chu-xuan(College of Veterinary Medicine,South China Agriculture University,Guangzhou 510642,China)

【机构】 华南农业大学兽医学院

【摘要】 鸭接种高致病力禽流感病毒A/duck/Guangdong/220/2004(H5N1)后,血清中的丙氨酸氨基转移酶(谷丙转氨酶)、天门冬氨酸氨基转移酶(谷草转氨酶)、γ-谷氨酰基转移酶、肌酸激酶和乳酸脱氢酶明显升高;碱性磷酸酶明显下降;α-淀粉酶先升高后下降;总蛋白、球蛋白、尿素氮、胆固醇、钙和磷轻微升高;白蛋白、肌酐、葡萄糖、甘油三酯和尿酸轻微下降。作者认为,检查这些血液生化指标的变化,对于诊断禽流感具有一定意义。

【Abstract】 Eighteen blood biochemical indexes were tested in ducks experimentally infected with a highly pathogenic avian influenza virus,A/duck/Guangdong/220/2004(H5N1) by intravenous and eyes-nares-mouth-cloaca routes.The results showed that the activity or contents of serum alanine aminotransferase(glutamic-pyruvic transminase),aspartate aminotransferase(glutamic-oxaloacetic transminase),γ-glutamyltransferase,creatine kinase,lactate dehydrogenase were significantly increased;alkaline phosphatase’s were obviously decreased;early α-Amylase’s were significantly increased,late slightly decreased;total protein,globin,urea nitrogen,cholesterol,calcium and phosphorus’s were somewhat increased;albumin,creatinine,glucose,triglycerides and uric acid’s were usually decreased.We consider that assaying these blood biochemical indexes are useful for diagnosing avian influenza.

【关键词】 H5N1亚型禽流感血液生化
【Key words】 H5N1 subtype avian influenzablood biochemistryducks
【基金】 广东省科技攻关项目(2004A2090102);广东省教育厅科学基金项目(Z02003)
  • 【文献出处】 中国畜牧兽医 ,China Animal Husbandry & Veterinary Medicine , 编辑部邮箱 ,2009年04期
  • 【分类号】S852.65
  • 【被引频次】7
  • 【下载频次】155
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