【摘要】 早产是围生儿并发症及死亡的主要原因之一。早产的预测是研究热点,大量文献分别从超声测量学角度,包括宫颈长度,胎儿某内脏的测量;宫颈阴道分泌物中多项指标,如胎儿纤维结合蛋白、磷酸化及脱磷酸化胰岛素样生长因子连接蛋白-1、白细胞介素的测定;血生化分析,如血清松弛肽、C反应蛋白、糖化血红蛋白含量的变化及羊水化验与感染有关的一些因子,如快速基质金属蛋白酶8、单核细胞趋化蛋白-1、γ干扰素诱导T细胞α趋化因子等,阐述各指标对早产的预测价值。以期找到更加稳定可靠的预测早产指标,提高围生质量。更多还原

【Abstract】 Preterm delivery is one of the main causes for perinatal complications and death.Many literatures focus on preterm prediction study and evaluate every predictor.The predictors include cervical length and the size of some of fetal organs measured by ultrasound;the level of fFN,IGFBP-1,IL investigated in cervicovaginal fluid,serum relaxin,CRP and HbA1c in mother’s blood,MMP-8,MCP-1 and ITAC in amniotic fluid which correlated with infection.The purpose of these studies is to find some more reliable factors to predict preterm delivery and improve the perinatal quality.更多还原