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甲状腺球蛋白抗体、甲状腺微粒体抗体不同条件下在血清中的稳定性

Thyroglobulin antibody(TGAb),thyroid microsomal antibodies(TMAb) under different conditions in the stability of the serum

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【作者】 郭永铁

【Author】 GUO Yong-tie.Tianjin University of Traditional Chinese Medicine First Affiliated Hospital Clinical Laboratory,Tianjin 300193,China

【机构】 天津中医药大学附属第一医院检验科

【摘要】 目的探讨甲状腺球蛋白抗体(TGAb)和甲状腺微粒体抗体(TMAb)不同条件下在血清中的稳定性。方法用放射免疫法测定放置室温、4℃冰箱、冰冻条件下,不同时间段血清样本中的TGAb与TMAb的活性。结果3种条件在储存2 d以后的结果差异无统计学意义;储存4 d后,室温条件下样品的TGAb与TMAb失活;储存6 d后,4℃冰箱条件下样品的TGAb与TMAb失活;储存29 d后,冰冻条件下样品的TGAb与TMAb失活。结论使用4℃冰箱保存4 d内的血样进一步作甲状腺抗体的检测,可以保证其准确性且又不影响日常临床工作。

【Abstract】 Objective To investigate the thyroglobulin antibody(TGAb) and thyroid microsomal antibodies (TMAb) under different conditions in the serum Stability.Methods Measured by radioimmunoassay place at room temperature,4℃refrigerator,ice conditions,the different time periods in serum samples of TGAb and TMAb activity.Results Three conditions in the storage Two days later the results of no significant difference;stored 4 days at room temperature samples TGAb and TMAb inactivation;storage 6 days,4℃refrigerator under the conditions of the samples TGAb and TMAb inactivation;store 29 days later,the frozen samples under the conditions of TGAb and TMAb inactivation.Conclusion 4℃refrigerator used to preserve blood samples for further screening for thyroid antibodies,the most suitable for day-to-day clinical work.

【关键词】 甲状腺球蛋白抗体微粒体
【Key words】 ThyroglobulinAntibodiesMicrosomes
  • 【文献出处】 国际检验医学杂志 ,International Journal of Laboratory Medicine , 编辑部邮箱 ,2009年05期
  • 【分类号】R817.4;R581
  • 【下载频次】7
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