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3 649例孕妇HBV、HCV、HIV和TPPA感染血清流行病学的分析

Analysis on serological epidemiology of HBV,HCV,HIV and TPPA infection in 3 649 pregnant women

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【作者】 林广玲黄林锋林少晖林美珊陈小凤

【Author】 LIN Guang-ling~1 HUANG Lin-feng~2 LIN Shao-Hui~1.1.The Second Affiliated Hospital,Medical College of Shantou University,Shantou 515000,China;2.The Second People’s Hospital of Shantou City,Shantou 515011,China

【机构】 广东省汕头大学医学院附属第二医院检验科广东省汕头市第二人民医院内科广东省汕头大学医学院附属第二医院信息科广东省汕头大学医学院附属第二医院产科

【摘要】 目的了解孕妇乙型肝炎病毒(HBV)、丙型肝炎病毒(HCV)、艾滋病毒(HIV)和梅毒感染情况,为建立有效的防治母婴传播措施提供依据。方法对来本院做围生保健3 649例孕妇,采用ELISA法检测血清5项乙肝标志物(HBsAg、抗-HBs、HBeAg、抗-HBe和抗-HBc)、抗-HCV、抗-HIV和梅毒血清学检测(TPPA)。结果 3 649例孕妇中,HBsAg阳性率为11.13%,抗-HCV和TPPA阳性率分别为0.11%和0.36%,未检测出抗-HIV阳性孕妇。结论揭示了本市孕妇HBV、HCV、HIV和TPPA感染血清流行病学特征,建议青年男女婚前、孕前、孕期、产前应进行HBV、HCV、HIV和TPPA血清学检查,才能及早发现、及早治疗,有效阻断母婴传播,有利于优生优育。

【Abstract】 Objective To investigate the infection status of HBV,HCV,HIV and microspi- ronema pallidum,and to provide theoretic basis for the prevention of intrauterine infection.Methods Enzyme linked immunosorbent assay (ELISA) was applied to measuring HBV marlers (HBsAg,anti- HBs,HBeAg,anti-HBe,and anti-HBc),anti-HCV,anti-HIV and treponema pallidum particle ag- glutination (TPPA) in 3 649 cases of pregnant women.Results The positive rate of HBsAg,anti- HCV and TPPA was 11.13%,0.11% and 0.36% respectively.No anti-HIV positive sample was found.Conclusion The result reveals the epidemiologic feature of HBV,HCV,HIV and microspi- ronema pallidum infection in pregnant women in the city,and it suggests that the serologic examina- tion of HBV,HCV,HIV and TPPA before marriage,progestation,duration of pregnancy and antep- artum be essential to early diagnosis and timely treatment,blockage of intrauterine infection as well as of aristogenesis.

  • 【文献出处】 国际检验医学杂志 ,International Journal of Laboratory Medicine , 编辑部邮箱 ,2009年03期
  • 【分类号】R446.61
  • 【被引频次】4
  • 【下载频次】4
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