【摘要】 目的探讨检测总蛋白（TP）、C-反应蛋白（CRP）、β₂-微球蛋白（β₂-m）在炎性与非炎性胸腹水鉴别诊断中的应用价值。方法测定220例胸腹水的TP、CRP、β₂-m,对检测结果分组进行统计学分析,并应用ROC曲线选择3项指标确定炎性胸腹水的鉴别临界值。结果3项指标在炎性和非炎性胸腹水鉴别差异均有统计学意义（P<0.01）,其ROC曲线下面积分别为胸水TP 0.8259、腹水TP0.8367、CRP0.8863、β₂-m 0.9365。鉴别临界值为胸水TP 30g/L、腹水TP 20g/L、CRP 24mg/L、β₂-m 3.2mg/L。结论TP、CRP、β₂-m都是炎性胸腹水鉴别诊断的良好指标。更多还原

【Abstract】 Objective To explore the applicable value of TP,CRP andβ₂-m in differential diagnosis of inflammatory and non-inflammatory hydrothorax and ascites.Methods The levels of total protein（TP）,C reactive protein（CRP） andβ₂-microglobulin（β₂-m） were measured in 220 cases of hydrothorax and ascites,and the results were statistically analyzed.The receiver operating characteristic （ROC） curve was applied to identifying the critical value of three indicators in differential diagnosis of inflammatory and non-inflammatory hydrothorax and ascites.Results There were significant differences in the three indicators of inflammatory and non-inflammatory hydrothorax and ascites（P 0.01）;the areas under ROC curve were hydrothorax TP 0.8259;ascites TP 0.8367,CRP 0.8863,β₂-m 0.9365.The critical values of differential diagnosis were hydrothorax TP 30 g/L,ascites TP 20 g/L,CRP 24 mg/L,β₂-m 3.2 mg/L.Conclusion The three markers（TP,CRP andβ₂-m） are all good indicators of differential diagnosis of inflammatory hydrothorax and ascites.更多还原