【摘要】 通过分析治疗胆囊炎、胆石症的蒙药苏斯—12中微量元素含量,探讨蒙药苏斯—12的药效与微量元素含量的关系。应用高压密封微波消解、电感耦合等离子体原子发射光谱法(ICP-AES)对蒙药苏斯—12进行微量元素含量分析。在蒙药的配制及整体研究工作中发现它们含有多种氨基酸和丰富的微量元素,实验结果表明:苏斯—12中含有丰富的微量元素,尤其Ca,Al,Mg,Fe,Sr,Mn,Zn,Cu等元素的含量比较高,而Pb,Cd,As等元素含量相对低,都低于国家限定值。加标回收率在94.63%～106.40%之间,相对标准偏差RSD≤3.35%,检出限在≤0.009μg·L-1。蒙药苏斯—12有效控制和治疗胆囊炎、胆石症,总有效率达91.2%和100%,蒙药苏斯—12中的微量元素与药效之间有密切的关系。更多还原

【Abstract】 Trace elements in Mongolian medicine Susi-12 for cholecystitis and gallstones were analyzed in order to discuss the relation between Susi-12’s drug action and the trace elements. The analysis was carried out using the pressure seal microwave digestion and inductive coupled plasma atomic emission spectrometry (ICP-AES). It was found that the medicine contained great amount of trace elements,especially human-body-needed trace elements,such as Ca,Al,Mg,Fe,Sr,Mn,Zn,Cu etc.,whereas heavy metals are very little,e.g. the contents of Pb,Cb,As etc are below the country’s limit. The recoveries of standard addition are in the range of 94.63%-106.40%. The relative standard deviation RSD≤3.35%,and detection limit is ≤0.009 mg·L-1. It is concluded that Mongolian medicine Susi-12 can effectively control and cure cholecystitis and gallstones,and the effective rate reaches 91.2% to 100%. So the trace elements in Susi-12 must have a close connection with the drug action.更多还原