【摘要】 目的调查住院患者双重及多重耐药菌感染的情况,提出控制措施。方法对某院2007年1月2008年12月住院的双重及多重耐药菌感染患者病历进行回顾性调查分析。结果 55 084例患者中,有1 436例(2.61%)查出有双重及多重耐药菌感染,其中社区获得性959例(1.74%),医院获得性477例(0.87%),两者之差异有显著性(x~2=323.571,P=0.000)。发生双重及多重耐药菌医院感染者占医院感染总人数的25.74%(1 853例),出现较多的科室是重症监护室(16.98%)、神经外科(14.67%)、烧伤外科(14.25%)、神经内科(14.04%)。感染部位以呼吸道为主(824例次,51.92%)。75.97%(1 091例)的双重及多重耐药菌感染者在感染前使用过抗菌药物。结论双重及多重耐药菌感染以社区获得较多。合理使用抗菌药物是控制和减少双重及多重耐药菌感染的主要措施。更多还原

【Abstract】 Objective To investigate infections with double and multiple drug-resistant bacteria in hospitalized patients, and to put forward control measures.Methods Medical histry of patients who were hospitalized between January,2007 and December,2008 were analysed retrospectively.Results Among 55 084 patients,1436 (2.61%) developed infections with double and multiple drug-resistant bacteria,959 (1.74%) of which were community-acquired infections,477(0.87%) were nosocomial infections,there was significant difference between the two (χ~2=323.571,P=0.000).Infection with double and multiple drug-resistant bacteria accounted for 25.74% (1 853 cases) of patients with nosocomial infection.Infection mainly occurred in patients in intensive care unit (16.98 %),department of neurosurgery (14.67 %),burn unit (14.25 %) and department of neurology (14.04 %). The main infection sites were respiratory tract (824 cases,51.92%).75.97% (1 091 cases) of patients received antimicrobial agents before developing infection.Conclusion Infections with double and multiple bacteria are mainly community acquired infection.Rational appplication of antimicrobial agents are the main strategies for controlling and reducing infection with double and multiple bacteria.更多还原