【摘要】 采用高速淬冷法制备了催化剂前体Ni-M-Al合金,经碱活化处理后得到改性骨架镍催化剂。将该催化剂用于对硝基乙酰苯胺(p-NAT)液相加氢制备对氨基乙酰苯胺(p-AAT)的反应。考察了溶剂、原料及催化剂用量、反应温度、系统压力对反应的影响,以及不同反应温度下p-NAT浓度与反应时间的关系曲线,并优化了反应条件。以甲醇为溶剂,在60℃,1.0MPa,m(催化剂)/m(p-NAT)=1/10时,反应24分钟,p-NAT的转化率为100%,p-AAT的选择性达99.5%。更多还原

【Abstract】 p-Nitroacetanilide (p-NAT) was hydrogenated to p-aminoacetanilide (p-AAT) using modified skeletal nickel (S-Ni) as catalyst.The modified S-Ni catalyst was prepared through activation treatment of rapidly quenched Ni-M-Al alloy precursor in NaOH solution.Effects of solvent,amount of catalyst and substrate,reaction temperature and pressure on the reaction,as well as concentration of p-NAT as a function of reaction time under different reaction temperatures,were studied.Under the optimized conditions (60℃,1.0 MPa,m(cat.)/m(p-NAT)=1/10 and methanol as solvent),99.5% selectivity of p-AAT with 100% p-NAT conversion was obtained in 24 minutes.更多还原