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宫颈上皮内瘤样病变的诊断及其治疗方式的选择

Diagnosis and treatment experience in cervical intraepithelial neoplasia

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【作者】 沈丹陈建英闫彩平周晓霞

【Author】 SHEN Dan,CHEN Jian-ying,YAN Cai-ping,ZHOU Xiao-xia(Department of Gynecology and Obstetrics,Zhuhai People’s Hospital,Zhuhai 519000,China)

【机构】 暨南大学医学院第三附属医院珠海市人民医院妇产科

【摘要】 目的探讨宫颈上皮内瘤样病变(CIN)的诊断方法及其治疗方式的选择。方法回顾性分析我院自2004年1月至2006年12月各类CIN患者122例进行的阴道镜下活检及宫颈电刀环切术(Leep)的病理诊断。结果CIN-Ⅰ术后病理诊断没有升级病例,与术前宫颈活检符合率为83.3%;CIN-Ⅱ术后病理诊断有8例升级为CIN-Ⅲ,10例降级为CIN-I,2例降为慢性宫颈炎;与术前宫颈活检诊断符合率为65.5%。CIN-Ⅲ术后病理诊断有1例升级为原位癌,3例降级为CIN-Ⅱ,与术前宫颈活检诊断符合率为79.2%;原位癌术后病理诊断有2例升级为浸润癌,2例降级为CIN-Ⅲ,与术前宫颈活检诊断符合率为60%。结论CIN治疗应根据患者的年龄,是否有生育要求,阴道镜下宫颈活检的分级,恰当而合理地选择手术方式。

【Abstract】 Objective To summarize the diagnosis and treatment experience of cervical intraepithelial neoplasia(CIN).Methods Clinicopathologic data of 122 patients with CIN were retrospectively analyzed in our hospital between January 2004 and December 2006.All patients underwent cervical biopsy and loop electrosurgical excision procedure(LEEP).Results The diagnose accordance rates between preoperative biopsy and postoperative pathology were 83.3%,65.5%,79.2% and 60%; upgrading cases were 0,8,1 and 2;and downgrading cases were 5,12,3 and 2 in CIN I,CIN Ⅱ,CIN Ⅲ and carcinoma in situ,respectively.Conclusion The proper operation method should be selected according to the patient’s age,procreation requirement and CIN grading.

  • 【文献出处】 广东医学院学报 ,Journal of Guangdong Medical College , 编辑部邮箱 ,2009年02期
  • 【分类号】R737.33
  • 【被引频次】2
  • 【下载频次】50
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