【摘要】 目的观察四妙勇安汤不同提取部位的抗炎作用。方法利用二甲苯致小鼠耳廓肿和大鼠琼脂性肉芽肿炎症模型,观察不同提取部位对炎症的影响。结果大孔树脂50%醇洗液部位对小鼠耳廓肿胀度有明显的抑制作用(P<0.05);对大鼠琼脂性肉芽肿也有明显的抑制作用(P<0.05,P<0.01),且呈一定的量效关系。结论四妙勇安汤大孔树脂50%醇洗液部位具有显著的抗炎作用。更多还原

【Abstract】 Objective To investigate the anti-inflammation effects of extractive fractions isolated from Simiaoyong’an decoction. Methods The anti-inflammation actions of extractive fractions were examined in acute inflammation model in mice and chronic inflammation model in rats. Results Extraction fraction isolated with macroporous resin+50% ethanol had obvious anti-inflammation action acute inflammation in mice (P<0.05);also had anti-inflammation action chronic inflammation in rats with obvious dosage-effect relationship (P<0.05,P<0.01). Conclusion Extractive fraction isolated with macroporous resin+50% ethanol had notable anti-inflammation actions.更多还原