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原发性肝癌TACE后并发急性肾功能衰竭临床分析

TACE-INDUCED ACUTE RENAL FAILURE IN PATIENTS WITH PRIMARY LIVER CANCER

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【作者】 曲增强张遂亮陈晓霞丁宁周海华张柏和吴孟超

【Author】 (QU Zeng-qiang,ZHANG Sui-liang,CHEN Xiao-xia,et al. Eastern Hepatobiliary Surgery Hospital,The Second Military Medical University,Shanghai 200438,China)

【机构】 第二军医大学附属东方肝胆外科医院

【摘要】 目的探讨肝癌介入治疗后引起急性肾功能衰竭(ARF)的原因、临床表现特点、预防及治疗。方法对6例肝癌患者因介入治疗所致的ARF的临床表现、实验室检查、治疗及转归进行回顾性分析、讨论。结果6例肝癌均为原发性肝癌,介入治疗后出现ARF的时间为术后5天以内。经以血液透析为主的临床综合治疗后,5例患者肾功能均能恢复正常,1例患者因并发脑梗塞临床死亡。结论肝癌介入治疗引起ARF的比例虽然小,但危害大,应引起重视。积极有效的临床观察与早期干预治疗可减少介入治疗后ARF的发生率,术后出现肉眼血尿及实验室尿常规改变,及早给予干预治疗,可提高病人的预后。一旦确诊ARF临床发生,及时进行血液透析是治疗的关键。

【Abstract】 Objective To discuss the clinical features treatment,prevention and the pathogenesis of transcatheter arterial chemoembolization (TACE)-induced acute renal failure(ARF).Methods Clinical features,treatment process and laboratory findings of 6 patients suffered from primary liver cancer with TACE-induced ARF were analyzed retrospectively.Results The 6 cases,presented as massive type. ARF were occurred in 5 days after the TACE. 5 cases were managed with hemodialysis simultaneously and got over soon,1 patient died of brain fag after hemodialysis simultaneously.Conclusion TACE can induce acute renal failure,although ARF in patients with liver cancer after TACE is uncommon.The possibility of TACE-induce ARF will be decreased when indications should be selected strictly,reasonable medication and renal function should be closely monitored in the susceptible patiens. Hemodialysis is key for the treatment.

  • 【文献出处】 肝胆外科杂志 ,Journal of Hepatobiliary Surgery , 编辑部邮箱 ,2009年04期
  • 【分类号】R735.7
  • 【被引频次】3
  • 【下载频次】119
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