【摘要】 设计合成一个柔性插入配体dcpip(dcpip=2–(2,3–环己烯基咪唑并[4,5-f]邻菲咯啉)及其钌(II)多吡啶配合物[Ru(bpy)2(dcpip)](ClO4)2(bpy=2,2’–联吡啶)和[Ru(phen)2(dcpip)](ClO4)2(phen=1,10–邻菲咯啉)。采用元素分析和质谱对其进行表征。用电子吸收光谱、荧光光谱和粘度测试研究配合物与DNA作用。研究结果表明,配合物与DNA之间通过插入作用结合。更多还原

【Abstract】 A new ligand dcpip and its ruthenium(II) complexes [Ru(bpy)2 (dcpip)]2+ (bpy = 2,2′-bipyridine) and [Ru(phen)2(dcpip)]2+ (phen = 1,10- phenanthroline, dcpip = 2-(2,3-cyclohexenyl)imidazo[4,5-f][1,10]phenanthroline) were synthesized and characterized by elemental analysis and mass spectra. The DNA-binding properties of these complexes were investigated by spectroscopic methods and viscosity measurement. The experimental results indicated that the two complexes interact with calf thymus DNA (CT-DNA) by intercalative mode.更多还原