【摘要】 目的建立血液中Cr、Cd、As、Tl和Pb的电感耦合等离子体质谱(ICP-MS)分析方法。方法血液采用微波消解仪进行处理,以115In元素作内标,使用ICP-MS方法对血液中Cr、Cd、As、Tl和Pb进行分析。结果方法检出限为0.00001～0.00249μg/L,准确度为90.1%～110.7%,精密度为4.0%～7.9%。结论建立的方法准确、快速、线性范围宽、灵敏度高,适用于Cr、Cd、As、Tl和Pb中毒案件的检测。更多还原

【Abstract】 Objective To establish an inductively coupled plasma mass spectrometry(ICP-MS) method for determination of Cr, Cd, As, Tl and Pb in blood. Methods The samples were digested by microwave di- gestion instrument. ICP-MS was applied to determine Cr, Cd, As, Tl and Pb in blood by using 115In as an internal standard. Results The limits of detection were in the range of 0.000 01-0.002 49 μg/L. The accu- racy of the method ranged from 90.1% to 110.7% and the precision ranged from 4.0% to 7.9%. Conclusion The method is accurate and rapid with superior sensitivity and linear range. It could be used in the poisoning cases caused by Cr, Cd, As, Tl and Pb.更多还原