【摘要】 目的:探讨三维快速扰相梯度回波(3D-FSPGR)序列MRI动态增强扫描和扩散加权成像(DWI)对肝内小结节病变的诊断价值。方法:对56例经US或CT检查发现肝内小结节的患者行常规MRI平扫、3D-FSPGR动态增强及DWI检查(SE-EPI技术,b值分别为0和800 s/mm2)。对比分析3D-FSPGR三期增强扫描(A组)、DWI(B组)及这2种方法联合应用(C组)在结节检出和定性诊断方面的价值。结果:在结节检出方面:A组检出61个结节,B组检出49个,C组检出72个,3组间差异有极显著性意义(χ2=27.72,P<0.01);A组与B组比较,差异无显著性意义(χ2=5.54,P>0.05);A组、B组分别与C组比较,差异均有显著性意义(χ2值分别为11.91和27.37,P<0.01)。在结节的定性诊断方面:在取得临床或病理证实的52个病例中,A组诊断正确36例(69.2%),C组为47例(90.4%),2组间差异有显著性意义(χ2=7.21,P<0.05)。结论:联合应用3D-FSPGR动态增强扫描和DWI对肝内小结节病灶的检出和诊断具有重要的临床应用价值。更多还原

【Abstract】 Objective:To study the value of 3D FSPGR dynamic enhanced MRI in combination with diffusion weighted imaging(DWI) in the diagnosis of intra-hepatic small nodular lesions.Methods:56 cases with intra-hepatic small nodular lesions detected by Utrasonography or CT were examined by routine conventional and 3D FSPGR dynamic enhanced MRI in combination with DWI(SE/EPI technique,b value as 0 and 800s/mm2 respectively).The values of detection and diagnosis of intra-hepatic small nodular lesion by 3D-FSPGR tri-phase enhanced MRI(group A),DWI(group B) and 3D-FSPGR tri-phase enhanced MRI in combination with DWI(group C) were compared and analyzed.Results:In the respect of detecting intra-hepatic small nodular lesions,61 intra-hepatic small nodular lesions were detected by(group A),49 lesions by(group B) and 72 lesions by(group C),significant statistical differences were existed(χ2=27.72,P<0.01).No statistical diffe-rence was existed between(group A) and(group B)(χ2=5.54,P>0.05).As(group A) as well as(group B) compared with(group C) separately,significant statistical difference were existed(χ2=11.91 and 27.37 respectively,P<0.01).In the respect of qualitative diagnosis of intra-hepatic small nodular lesions,there were 52 clinical or pathology proved nodular lesions,correct diagnosis was obtained in 36 cases(69.2%) by(group A),47cases(90.4%) by(group C),with significant statistical difference(χ2=7.21).Conclusion:3D-FSPGR dynamic enhanced MRI in combination with DWI showed important clinical value in the aspects of detecting and diagnosis of intra-hepatic small nodular lesions.更多还原