【摘要】 【目的】了解1997~2008年出生缺陷对北京市海淀区户籍人口围产儿死亡的影响。【方法】资料来源于北京市围产儿死亡监测网,采用以人群为基础的监测方法。【结果】1997~2008年海淀区户籍围产儿死亡率5.96‰,出生缺陷造成的围产儿死亡占围产儿死亡37.50%,围产儿死亡率、出生缺陷死亡专率呈下降趋势。围产儿死亡中的出生缺陷顺位为先心病(18.7%)、多发畸形(15.1%)、总唇裂(11.1%)、脑积水(6.7%)、神经管畸形和染色体畸形(4.4%),可以避免和创造条件可以避免的比例为23.7%,"个人或家庭知识态度"是出生缺陷造成的围产儿死亡的第一位死因。【结论】海淀区围产儿死亡率稍低于北京市水平,低于全国水平;出生缺陷导致的围产儿死亡比例高于全国水平,与发达国家相当。更多还原

【Abstract】 【Objective】To understand the impacts of birth defects on perinatal mortality from 1997 to 2008 in Hai dian district in Beijing. 【Method】Data were derived from Beijing perinatal monitoring network-a community based perinatal mortality registry system. 【Results】Average perinatal mortality rate was 5.96 per 1 000 from 1997 to 2008 in Haidian district in Beijing.The proportion of perinatal mortality due to birth defects was 37.50%.The perinatal mortality rate and the perinatal birth defects-specific mortality rate showed downward trend.In the perinatal death,the major birth defects were congenital heart diseases,multiple defects,cleft lip with or without cleft palate,hydrocephaly,neural tube defects and chromosomal anomalies.The proportion of the avoidable death and possibly avoidable death was 23.7%.The first reason for the perinatal death due to birth defects was the attitude of the family to the birth defects’. 【Conclusions】The perinatal mortality rate in Haidian district is a little lower than that in Beijing,much lower than that in China.The proportion of perinatal mortality due to birth defects is much higher than that in China,and at the same level in developed countries.更多还原