【摘要】 【目的】检测产妇以及脐带血中维生素A,E,C以及β-胡萝卜素的含量并分析其与新生儿出生结果的关系。【方法】分娩后立即收集1 6 6对产妇和脐带血并利用HPLC法分别没定各种抗氧化维生素浓度,同时测定新生儿的身长、体重和头围。【结果】多元逐步回归分析显示产妇维生素A水平每升高1μmol/L,出生体重下降2 4.2 g(9 5%CI:-4 1.5~-5.9,P<0.01);维生素A胎盘转运率每增加1%,出生身长增加0.8 cm(9 5%CI:0.004~1.639,P=0.049)。产妇β-胡萝卜素水平每升高1μmol/L,出生体重增加12.4 g(9 5%CI:7.1~25.3,P=0.024)、出生身长增加约0.6 cm(9 5%CI:0.01~1.2 1,P=0.032)。【结论】孕期维生素A、β-胡萝卜素水平与新生儿发育水平具有相关性。更多还原

【Abstract】 【Objective】To measure the concentrations of vitamin A,E,C and β-carotene in maternal and cord blood and analysis the relationship between the levels of antioxidant vitamins and birth outcomes. 【Methods】A total of 166 matched maternal-neonate pairs were recruited into the cross-sectional descriptive study demographic information was investigated by questionnaire.After delivery,cord and maternal blood were collected to measure serum antioxidant vitamins by HPLC. 【Results】Each increase of 1 μmol/L unit in maternal vitamin A status was associated with a reduction of 24.2 grammas(95% CI:-41.5~-5.9) in brith weight(P<0.01) and every elevation of 1% unit of the vitamin A placenta transfer was accompanied with 0.8 cm(95% CI:0.004~1.639,P=0.049) increase of birth length.Moreover,each increase of 1 μmol/L unit in maternal β-carotene status was associated with elevations of 12.4 g(95% CI:7.1~25.3,P=0.024 1) in brith weight and 0.6 cm(95% CI:0.01~1.21,P=0.032) in brith length. 【Conclusion】Maternal vitamin A and β-carotene status at delivery had significant correlation birth length outcomes.更多还原