【摘要】 在嗅球生理解剖结构的基础上,首次建立了结构相对完整的球旁细胞(PG)、僧帽细胞(MC)和颗粒细胞(GC)离子通道及其细胞网络树树突触联结中神经递质传导的神经电生理网络模型.模型初步揭示了嗅球对来自于嗅感觉神经元电信号的瞬时同步时空编码机制以及嗅球的气味分辨机制,为下一步定量地探索研究PG、MC和GC细胞在嗅球编码中的不同作用机制,以及基于嗅球生理结构的气味模式识别的研究打下了基础.更多还原

【Abstract】 On the basis of the bulb physiological anatomic structure,a comparatively integrated bulb neural electrophysiological model incorporating periglomerular cells(PG),mitral cells(MC) and granule cells(GC) is constructed here originally by means of their ion channels and neurotransmitters among the dendrodendritic synapses in the neural cell network.This model preliminarily reveals the mechanisms of spatiotemporal coding of the odor information from olfactory sensory neurons and odor recognization of the bulb.It lays a good foundation for the further studies of the different mechanisms of PG,MC and GC cells in olfactory bulb coding as well as the odor pattern recognization based on the bulb physiological structure.更多还原