【摘要】 目的了解沿海居民高尿酸血症与心脑血管疾病的关系,为当地代谢性疾病及心脑血管病的防治提供依据。方法对在横栏医院参加年度体检的当地沿海居民3111例,进行(SUA)血尿酸水平及其相关危险因素的调查。按血尿酸水平分高尿酸血症组及对照组。对比分析两组间相关危险因素及心脑血管病的发病率的差别。结果①男性血尿酸均值在(380.2±62.58)μmol/L,女性为(290.82±60.32)μmlo/L;高尿酸血症患病率男性21.8%,女性17.6%,男性高尿酸血症患病率明显高于女性,有显著性差异(P<0.01);②血清尿酸与总胆固醇、甘油三酯、血压及体重指数呈正相关,超重/肥胖者血尿酸水平显著高于正常体重者;各种心血管危险因素在该人群中有聚集现象且有年轻化的趋势。结论①中山市沿海地区居民高尿酸血症患病率较高,且与多种因素有关,而居民知晓率较低,应采取综合措施进行防治,以降低患病率;②血清尿酸水平升高可能成为心脑血管病发生、发展的独立危险因素和预测因子,控制高尿酸血症的发生,可减少当地代谢性疾病及心脑血管病的患病率。更多还原

【Abstract】 Objetive To investigate the relationship between cardiac Cerebrovascular disease and serum uric acid(SUA) in the coastal inhabitant, and try to provide base for preventint of the local metabolic disease and cardiac Cerebrovascular disease. Methods We got 3111 local people who had participated in the annual physical examination in the perch hospital for the research on the level of SUA and the relative risk factor. According to SUA level we divided the cases into two groups. One is hyperuricemia group and the other is control group. Results ①The average SUA level was (380.2±62.58) μmol/L in the males, while (290.82±60.32) μmlo/L in the female. The sick rate of hyperuricaemia rate, was 21.8% for male, and the 17.6% ofr female. This disease more altaevied men than women. It has significant difference (P<0.01); ②The SUA level of the showed a positive correlation with the indexes of the total cholesterol, the triglyceride, the blood pressure and the body weight index. The SUA level in overweight/obesity people was obviously higher than that of the normal weight people. Conclusion ①The sick rate of hyperuricaemia is high in Zhongshan coastal area,which due to many related factors.As far as,few people know it, so we should adopt the synthesis measure to prevent and control it to reduce the sick rate;②the rise of The SUA level possibly becomes one of the independent dangerous and predictive factor for the heart cerebral von disease .更多还原