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基于互信息与梯度相似性相结合的医学图像配准方法

Medical image registration based on mutual information combined with gradient similarity

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【作者】 陈伟卿欧宗瑛李冠华韩军赵德伟王卫明

【Author】 CHEN Wei-qing1,2,OU Zong-ying*1,2,LI Guan-hua1,2,HAN Jun3,ZHAO De-wei4,WANG Wei-ming4(1.CAD&CG Laboratory,School of Mechanical Engineering,Dalian University of Technology,Dalian 116024,China;2.Key Laboratory for Precision & Non-traditional Machining Technology of Ministry of Education, Dalian University of Technology,Dalian 116024,China;3.Dalian Modern High Technology Development Cooperation Limited,Dalian 116021,China;4.Affiliated Zhongshan Hospital of Dalian University,Dalian 116001,China)

【机构】 大连理工大学机械工程学院CAD&CG研究所大连理工大学精密与特种加工教育部重点实验室大连现代高技术发展有限公司大连大学附属中山医院

【摘要】 针对传统互信息配准方法未利用图像空间信息的缺点,提出一种将互信息与梯度相似性结合的医学图像配准方法.待配准图像的每组对应点的梯度相似性包括方向相似性和模值相似性.待配准图像整体梯度相似性系数由各对应点对的梯度相似性之和决定,该系数与传统互信息的乘积作为图像配准的测度.利用2D多模图像分别进行平移、旋转、采样,得到配准函数曲线,并给出具体的配准实例.实验结果表明,该方法比传统互信息有更高的鲁棒性和精度.

【Abstract】 To solve the drawback that typical mutual information-based registration neglects the spatial information of images,a new medical image registration method is developed by combining mutual information with gradient similarity.The gradient similarity of each pair of corresponding points includes direction similarity and module similarity.The summation of the similarity term for all sample pairs gives the gradient similarity of two registration images,which is multiplied by the mutual information to form the final registration metric.Registration functions are analyzed and compared,applying in different transform such as translation,rotation and sub-sampling of 2D multi-modal images,respectively.Experimental results show that the new method performs better than typical mutual information in robustness and precision.

【基金】 “八六三”国家高技术研究发展计划资助项目(863-306-ZD13-03-6);大连市科技局科技计划资助项目(2005E21SF134)
  • 【文献出处】 大连理工大学学报 ,Journal of Dalian University of Technology , 编辑部邮箱 ,2009年03期
  • 【分类号】TP391.41
  • 【被引频次】10
  • 【下载频次】351
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