【摘要】 目的:探讨下尿路梗阻与膀胱肿瘤发病的相关性。方法:对272例次保留膀胱手术的患者进行多因素相关性分析,并对其中明显伴有下尿路梗阻的88例次患者.采用不同手术后的肿痛复发情况进行统计分析。结果:经逐步Logistic回归,显示肿瘸患者的年龄,最大尿流率,手术方式,膀胱灌注化疗与术后肿瘤复发有相关性,具统计学意义。TUR-Bt+TURP(BNI)36例次,6例次复发,复发率16.7%:膀胱部分切除术48例次,19例次复发,复发率39.6%。两种术式术后的复发率有明显的统计学差异(P<0.05)。结论:下排尿梗阻与膀胱肿瘤复发有明显的相关性,手术同时解除梗阻能显著降低膀胱肿瘤的复发。更多还原

【Abstract】 Objective:To study the correlation between recurrence of bladder tumor after surgical ablation and lower ureteric obstruction. Methods: 272 cases wore analysed by multivariate logistic regression analysis, and 88 cases with obviously lower ureteric obstruction were treated with different operations, the recurrrence rate were showed by statistical analysis between these two groups. Results: The multiple logistic regression analysis showed that there were 4 correlated influencing factors for age, maximum flow rate (MFR), operation style and intravesical chemotherapy. TUR-Bt combined TURP(or BNI)for 36 cases, tumor recurrence occured in 6 (16.7%); partial cystectomy for 48, tumor recurrence oeeured in 19(39.6%), statistical significant difference was found in the recurrence rate between these two groups (x~2=4.815,P<0.05). Conclusion: It is high correlation between recurrence of bladder tumor after surgical ablation and lower ureteric obstruction. Relief of ureteric obstruction would decrese recurrence rate of bladder cancer.更多还原